Dr Chen completed his postdoctoral training at the University of Utah and has over 20 years of work experience in the pharmaceutical industry. He has extensive experience in new drug research, discovery, and clinical development for indications such as osteoporosis, osteoarthritis, metastatic bone disease and oncology.
He used to be a Senior Scientist in the R&D Department at the headquarters of Merck & Co., Inc. During his 10-year tenure, he was mainly responsible for the clinical trials (Phase I and Phase III) of project products Odanacatib and MK-0764. To date, the drug Odanacatib completed Phase II trials for the treatment of metastatic bone disease (MBD) in 2008 and Phase III clinical trials for the treatment of osteoporosis in 2016; the drug MK-0764 completed Phase III clinical trials for the treatment of osteoarthritis in 2017. He has published a total of 4 papers on the research results of these projects in journals including <JBMR>, <Bone>, and <Bone Report>.
Dr Chen has also participated in the preparation of WMA (World Market Application) documents for the Odanacatib product, making significant contributions to the registration of Odanacatib in multiple countries.
Dr. Jiang earned his Ph.D. in Medicinal Chemistry from the Shanghai Institute of Materia Medica, Chinese Academy of Sciences, followed by postdoctoral training at Oregon Health & Science University (OHSU) in the U.S. and served as a Visiting Professor at the University of California, Davis (UC Davis). He has been recognized as a Shanghai Oriental Talent (Leading Talent) and is a recipient of the Shanghai Talent Development Fund.
Dr Nancy E. Lane is the Leader of the Regenerative Medicine R&D Team in the United States, an Elected Member of the National Academy of Medicine (USA), and one of the key inventors of the novel drug LLP2A-Ale (RAB001). Internationally renowned, Dr. Lane is a preeminent scientist in the fields of osteoporosis and osteoarthritis.
Dr. Lane previously chaired the Board of Directors of the U.S. Bone and Joint Decade Initiative (now known as the Decade of Bone and Joint Initiative). She is an Elected Member of the American Association for the Advancement of Science (AAAS) Council and has held leadership positions within the American Society for Bone and Mineral Research (ASBMR) and the Orthopaedic Research Society (ORS). Dr. Lane also serves as Associate Editor for *Nature Reviews Rheumatology* and *Seminars in Arthritis and Rheumatism*, and as an Editorial Board Member of *The Journal of Rheumatology*.
Her distinctions include being an Elected Member of the Association of American Physicians (AAP) and the Institute of Medicine (IOM) of the National Academies (now part of the National Academy of Medicine). She has been consistently recognized as one of America's Top Doctors® annually since 2004 in the specialty of Rheumatology.
Fred M. Tileston Jr., CEO of RABOME (USA), graduated from Stanford University with a Bachelor's degree in Industrial Engineering, an MBA in Marketing and Finance, a Doctor of Laws degree, and a lawyer's license. He is a senior management talent in business development and start-ups, specializing in company establishment, sales arrangements, investment and financing, as well as international law and economic law. He is a member of the State Bar of California and has 40 years of extensive experience in business operations such as helping client companies start up, conduct marketing, sell products, and formulate strategic plans for large and medium-sized enterprises. His professional fields include business plan writing, business development, structured financing, agreement negotiation, and company acquisition/sale.
The Bone and Joint Regenerative Medicine Co., Ltd. (RABOME), founded by Mr. Fred M. Tileston Jr. and Mr. Chen Jiwei, is headquartered in San Francisco, USA. It is a world-leading company with biopharmaceutical technology R&D capabilities and technology platforms. Relying on the University of California, Davis, it has built a world-class biomedical laboratory and a team of American academician scientists and internationally renowned consultants. With years of R&D experience in the field of osteology, the company has established long-term and stable cooperative relationships with world-renowned pharmaceutical companies, biotechnology companies, hospitals and famous universities around the world to carry out cooperation in various osteological projects.
